Introducing the Nadia Innovate – the open platform for single cell research and development Live webinar, 24 June 2021 |3PM SGT | UTC+8 Register now In recent years, new single cell technologies have revolutionized our understanding of cell identity and ...
Read More »Optimize Your Single Cell Research – Best Techniques for Sample Preparation
Optimize Your Single Cell Research – Best Techniques for Sample Preparation Session 1 Webinar: Optimize Your Single Cell Research: Best Techniques for Sample Preparation Date: 26.05.2021 Time: 10 CET | 9 GMT Session 2 Webinar: Optimize Your Single Cell Research: ...
Read More »SparK: Publication-Quality NGS plotting tool
While there are sophisticated resources available for displaying NGS data, including the Integrative Genomics Viewer (IGV) and the UCSC genome browser, exporting regions and assembling figures for publication remains challenging. In particular, customizing track appearance and overlaying track replicates is ...
Read More »REcount – measuring sequencer size bias using
Quantification of DNA sequence tags from engineered constructs such as plasmids, transposons, or other transgenes underlies many functional genomics measurements. Typically, such measurements rely on PCR followed by next...
Read More »Upcoming Webinar – ChIP-Seq / ATAC-Seq Analysis and Integration with Gene Expression Data
ChIP-Seq / ATAC-Seq Analysis and Integration with Gene Expression Data ChIP-Seq and ATAC-Seq empower researchers to learn how gene expression is regulated by transcription factors, histone modifications, and chromatin accessibility. But processing and analyzing the data can be difficult. In ...
Read More »CSBB – Computational Suite for Bioinformaticians and Biologists
Version3.0 is now available for download !! Download CSBB-v3.0 from GitHub or Source Forge : GitHub : https://github.com/csbbcompbio/CSBB-v3.0 Source Forge: https://sourceforge.net/projects/csbb-v3-0/?source=navbar Major Highlights of version 3.0: *RNA-Seq processing for human, mouse, frog and zebrafish *ChIP-Seq processing for human, mouse and frog *ATAC-Seq ...
Read More »Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes
Highlights Defined open chromatin regions in sorted human α- and β-cells using ATAC-seq. Detected type 2 diabetes-associated risk loci in human α- and β-cell open chromatin. Classified human α- and β-cell-specific transcripts using mRNA-seq. Discovered novel ...
Read More »BIRD – Global Prediction of Chromatin Accessibility Using RNA-seq from Small Number of Cells
Conventional high-throughput technologies for mapping regulatory element activities such as ChIP-seq, DNase-seq and FAIRE-seq cannot analyze samples with small number of cells. The recently developed ATAC-seq allows regulome mapping in small-cell-number samples, but its signal in single cell or samples ...
Read More »Fine-mapping cellular QTLs with RASQUAL and ATAC-seq
When cellular traits are measured using high-throughput DNA sequencing, quantitative trait loci (QTLs) manifest as fragment count differences between individuals and allelic differences within individuals. Researchers from the Wellcome Trust Sanger Institute have developed RASQUAL (Robust Allele-Specific Quantitation and Quality Control), ...
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