Researchers from Stefan Kubicek's and Christoph Bock’s groups, at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna, have developed a method to...
Read More »Novel small RNA spike-in oligonucleotides enable absolute normalization of small RNA-Seq data
Normalization of high-throughput small RNA sequencing (sRNA-Seq) data is required to compare sRNA levels across different samples. Commonly used relative normalization approaches can cause erroneous conclusions due to fluctuating small RNA populations between tissues. Researchers from the Austrian Academy of ...
Read More »CRISPR meets single-cell RNA sequencing in new screening method
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences Genome editing using CRISPR/Cas9 “gene scissors” is a powerful tool for biological discovery and for identifying novel drug targets. In pooled CRISPR screens, a large number of cells ...
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