As an international collaboration between hardware and middleware engineers at Earlham Institute, support staff in the Norwich Research Park Computing Infrastructure for Science (NRP CiS) team, University of Arizona, Texas Advanced Computing Centre and Cold Spring Harbor Labs, CyVerse UK ...
Read More »SAMSA – a comprehensive metatranscriptome analysis pipeline
Although metatranscriptomics-the study of diverse microbial population activity based on RNA-seq data-is rapidly growing in popularity, there are limited options for biologists to analyze this type of data. Current approaches for processing metatranscriptomes rely on restricted databases and a dedicated ...
Read More »Moon Shots Program APOLLO Project to Perform DNA / RNA-Seq on Serial Biopsies
Biopsies before, during, after therapy and deep molecular analysis seek tumor tricks to target A study that indicates how advanced melanoma responds to an immunotherapy, published in Cancer Discovery, demonstrates a revolutionary approach from The University of Texas MD Anderson ...
Read More »Integration of RNA-Seq Big Data in Bgee Interface
How to not throw away Terabytes of publicly-funded data: integration of RNA-Seq big data in Bgee Frédéric Bastian, Evolutionary Bioinformatics, Lausanne Bgee Interface
Read More »Using big data, scientists discover biomarkers that could help give cancer patients better survival estimates
A SURVIV analysis of breast cancer isoforms developed at UCLA. Blue lines are associated with longer survival times, and magenta lines with shorter survival times. People with cancer are often told by their doctors approximately how long they have to ...
Read More »The FDA weighs in on RNA-Seq
The rapid advancement of emerging genomics technologies and their application for assessing safety and efficacy of FDA-regulated products require a high standard of reliability and robustness supporting regulatory decision-making in the FDA. To facilitate the regulatory application, the FDA implemented ...
Read More »Workflow of inter-institutional scRNA-seq big data integration
The rapid growth of single-cell RNA-seq studies (scRNA-seq) demands efficient data storage, processing, and analysis. Big-data technology provides a framework that facilitates the comprehensive discovery of biological signals from inter-institutional scRNA-seq datasets. There are several strategies to solve the stochastic ...
Read More »Advanced Workshop for SRA & dbGaP Users
Presented March 23, 2016. This webinar is for those who have experience with RNA-Seq analysis, variant calling or metagenomic data and want to work with large genomic datasets, use cloud computing for analyzing genomic datasets and perform parallel work on ...
Read More »Comprehensive Assessments of RNA-seq by the SEQC Consortium
Studies on gene expression in response to therapy have led to the discovery of pharmacogenomics biomarkers and advances in precision medicine. Whole transcriptome sequencing (RNA-seq) is an emerging tool for profiling gene expression and has received wide adoption in the ...
Read More »GeneAnalytics – An Integrative Gene Set Analysis Tool for Next Generation Sequencing, RNAseq and Microarray Data
Postgenomics data are produced in large volumes by life sciences and clinical applications of novel omics diagnostics and therapeutics for precision medicine. To move from “data-to-knowledge-to-innovation,” a crucial missing step in the current era is, however, our limited understanding of ...
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