Differential transcript usage from RNA-seq data – isoform pre-filtering improves performance of count-based methods

August 27, 2015 Leave a comment 5,443 Views

Large-scale sequencing of cDNA (RNA-seq) has been a boon to the quantitative analysis of transcriptomes. A notable application is the detection of changes in transcript usage between experimental conditions. For example, discovery of pathological alternative splicing may allow the development ...

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