Tag Archives: biological variation

Previous comparisons between microarrays and RNA-Seq have come to sometimes contradictory conclusions, which researchers from Princeton University suggest result from a lack of attention to the intensity-dependent nature of variation generated by the technologies. To examine this trend, they carried ...

RNA-seq has become a routine technique in differential expression (DE) identification. Scientists face a number of experimental design decisions including the sample size. The power for detecting differential expression is affected by several factors including the fraction of DE genes, ...

RNA-sequencing data analysis method BitSeq developed by Academy Research Fellow Antti Honkela?s research group and University of Manchester researchers has been found to be the most accurate gene transcript expression estimation method in a large international assessment. The method is ...