Tag Archives: biomarker

Histopathology-based staging of colorectal cancer (CRC) has utility in assessing the prognosis of patient subtypes, but as yet cannot accurately predict individual patient’s treatment response. Transcriptomics approaches, using array based or next generation sequencing (NGS) platforms, of formalin fixed paraffin ...

Pulmonary Fibrosis News – by Pais Teresa – Researchers have identified 39 genes as critical to idiopathic pulmonary fibrosis (IPF), based on a computational analysis of large genomic studies. Their study, “Detecting the Molecular System Signatures of Idiopathic Pulmonary Fibrosis through Integrated Genomic ...

Small RNA-Seq has emerged as a powerful tool in transcriptomics, gene expression profiling and biomarker discovery. Sequencing cell-free nucleic acids, particularly microRNA (miRNA), from liquid biopsies additionally provides exciting possibilities for molecular diagnostics, and might help establish disease-specific biomarker signatures. ...

Exosome Diagnostics, Inc. in recent partnership with Takeda Pharmaceuticals has produced the industry’s first data demonstrating the power of exosomal RNA (exoRNA) for long RNA sequencing (RNA-Seq). This discovery will enable insight into a patient’s genetic makeup that was previously ...

qPCR dPCR & NGS 2017 Liquid Biopsy, Integrative Big Data Analysis, Biomarker Signature … and beyond Symposium  &  Industrial Exhibition  &  Application Workshops 3 – 7 April 2017,   in Freising-Weihenstephan, School of Life Sciences, Technical University of Munich, Weihenstephan, ...

Small RNA-Seq has emerged as a powerful tool in transcriptomics, gene expression profiling and biomarker discovery. Sequencing cell-free nucleic acids, particularly microRNA (miRNA), from liquid biopsies additionally provides exciting possibilities for molecular diagnostics, and might help establish disease-specific biomarker signatures. ...

MicroRNAs (miRNAs) play important roles in cellular functions and developmental processes. They are also implicated in oncogenesis mechanisms and could serve as potential cancer biomarkers. Using high-throughput miRNA sequencing information, expression of both the 5p-arm and 3p-arm mature miRNAs were ...

Recent comprehensive assessments of RNA-seq technology support its utility in quantifying gene expression in various samples. The next step of rigorously quantifying differences between sample groups, however, still lacks well-defined best practices. Although a number of advanced statistical methods have ...

from GenomeWeb NEW YORK (GenomeWeb) – Sperm RNA could be used as a biomarker diagnose male fertility, according to a new paper published today in Science Translational Medicine. Scientists led by Meritxell Jodar and Stephen Krawetz of Wayne State University ...

UCLA life scientists have created an accurate new method to identify genetic markers for many diseases — a significant step toward a new era of personalized medicine, tailored to each person’s DNA and RNA. The powerful method, called GIREMI (pronounced ...