RNA-Seq Blog Transcriptome Research & Industry News
Fusion genes are both useful cancer biomarkers and important drug targets. Finding relevant fusion genes is challenging due to genomic instability resulting in a high number of passenger events...
Read More »FUNGI – Fusion Gene Integration Toolset
Researchers use RNA Sequencing to track down molecular signals of Parkinson’s disease
Parkinson’s disease is the second most common neurodegenerative disease in the world, yet little is known about its causes and progression...
Read More »New research identifies circulating RNA preeclampsia biomarkers
Researchers at Illumina and several universities have shown that sequencing circulating RNA (C-RNA) can detect molecular signals of preeclampsia in the blood. Published in Science Translational Medicine...
Read More »Collaboration will demonstrate the powerful advantages of transcriptomic data analysis for prediction of the response to novel cancer therapies
BostonGene Corporation, a biomedical software company committed to defining optimal precision medicine-based therapies for cancer patients, today announced a scientific collaboration with Brigham and Women’s Hospital, a world-class academic medical center and a major teaching hospital of Harvard Medical School ...
Read More »RNA Sequencing uncovers diagnostic biomarkers for rare kidney cancer
U-M study combines local data with data from The Cancer Genome Atlas to discover novel biomarkers for chromophobe renal cell carcinoma through...
Read More »A digital cell sorter for identification of cell types from single cell RNA-sequencing clusters
Single cell RNA sequencing (scRNA-seq) brings unprecedented opportunities for mapping the heterogeneity of complex cellular environments such as bone marrow, and provides insight into many cellular processes. Single cell RNA-seq has a far larger fraction of missing data reported as ...
Read More »RNA-Seq reveals the long noncoding RNA landscape of neuroendocrine prostate cancer and its clinical implications
To date, a comprehensive characterization of the dynamic landscape of lncRNAs during the neuroendocrine transdifferentiation (NEtD) process has not been performed. A temporal analysis of the...
Read More »A RNA-Sequencing approach for the identification of novel long non-coding RNA biomarkers in colorectal cancer
Long non-coding RNAs (lncRNAs) have been implicated in human pathology, however, their role in colorectal carcinogenesis have not been fully elucidated. In the current study, researchers from Baylor...
Read More »An NGS assay to quantify biomarkers of the host immune response in FFPE tumor samples
OmniSeq Inc scientists have developed a next-generation sequencing assay to quantify biomarkers of the host immune response in formalin-fixed, paraffin-embedded (FFPE) tumor specimens. This assay aims to provide clinicians with a comprehensive characterization of the immunological tumor microenvironment as a ...
Read More »confFuse – high-confidence fusion gene detection
Fusion genes play an important role in the tumorigenesis of many cancers. Next-generation sequencing (NGS) technologies have been successfully applied in fusion gene detection for the last several years, and a number of NGS-based tools have been developed for identifying ...
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