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Tag Archives: Blood disorders

Researchers use AI, RNA-Seq to unlock the secrets of the genome

December 28, 2017 Leave a comment 3,942 Views

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Every nine minutes, someone in the US dies from blood cancer which accounts for about 10 percent of all cancer deaths. And, every three minutes, one person in the US is diagnosed with a blood cancer — about 170,000 people ...

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Recent RNA-SEQ Pubs

Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones
8 March 2021
Therapeutic implications of <em>C. albicans-S. aureus</em> mixed biofilm in a murine subcutaneous catheter model of polymicrobial infection
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Sex-Specific Control of Human Heart Maturation by the Progesterone Receptor
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Eleven biosynthetic genes explain the majority of natural variation in carotenoid levels in maize grain
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Knowledge-based classification of fine-grained immune cell types in single-cell RNA-Seq data
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A de Novo Transcriptome Assembly of Ceratopteris Richardii Provides Insights into the Evolutionary Dynamics of Complex Gene Families in Land Plants
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What is RNA-Seq?

long RNAs are first converted into a library of cDNA fragments through either RNA fragmentation or DNA fragmentation. Sequencing adaptors (blue) are subsequently added to each cDNA fragment and a short sequence is obtained from each cDNA using high-throughput sequencing technology. The resulting sequence reads are aligned with the reference genome or transcriptome, and classified as three types: exonic reads, junction reads and poly(A) end-reads. These three types are used to generate a base-resolution expression profile for each gene. Nat Rev Genet 10(1):57-63 (2009)


RNA-Seq

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    Learn more about available bioinformatics tools and pipelines to analyze RNA sequencing data

    4 days ago
  • rna-seq

    New search engine for single cell atlases

    4 days ago
  • rna-seq

    Yale researchers identify tumor reactive immune cells with RNA sequencing to help fight against advanced melanoma

    4 days ago
  • rna-seq

    New algorithm identifies ‘escaping’ cells in single-cell CRISPR screens

    5 days ago
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    Uncovering the Anti-Myeloma Resistance Files

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