Fast Bootstrapping-Based Estimation of Confidence Intervals of Expression Levels and Differential Expression from RNA-Seq Data

June 15, 2017 Leave a comment 3,680 Views

Researchers from Georgia State University present IsoEM2 and IsoDE2, new versions with enhanced features and faster runtime of the IsoEM and IsoDE packages for expression level estimation and differential expression. IsoEM2 estimates FPKM and TPM levels for genes and isoforms ...

Differential analysis of RNA-seq incorporating quantification uncertainty

June 7, 2017 Leave a comment 5,397 Views

Caltech researchers describe sleuth, a method for the differential analysis of gene expression data that utilizes bootstrapping in conjunction with response error linear modeling to decouple biological variance from inferential variance. sleuth is implemented in an interactive shiny app that ...

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Fast Bootstrapping-Based Estimation of Confidence Intervals of Expression Levels and Differential Expression from RNA-Seq Data

Differential analysis of RNA-seq incorporating quantification uncertainty

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