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Tag Archives: bowel tumour

Single cell RNA-Seq technology and organoids reveal every bowel tumour and bowel cancer cell have unique genetic fingerprints

April 18, 2018 Leave a comment 3,143 Views

rna-seq

Study could help researchers target cancer-specific processes for cancer prevention or to develop treatments New research on bowel cancer has shown that every tumour is different, and that every cell within the tumour is also genetically unique. In the first ...

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Recent RNA-SEQ Pubs

Network pharmacology and RNA-sequencing reveal the molecular mechanism of Xuebijing injection on COVID-19-induced cardiac dysfunction
4 March 2021
Direct Comparative Analyses of 10X Genomics Chromium and Smart-seq2
4 March 2021
Metabolic adjustments during starvation in Daphnia pulex
4 March 2021
SwarnSeq: An improved statistical approach for differential expression analysis of single-cell RNA-seq data
4 March 2021
The overexpression of DNA repair genes in invasive ductal and lobular breast carcinomas: Insights on individual variations and precision medicine
4 March 2021
Detecting cell-type-specific allelic expression imbalance by integrative analysis of bulk and single-cell RNA sequencing data
4 March 2021

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What is RNA-Seq?

long RNAs are first converted into a library of cDNA fragments through either RNA fragmentation or DNA fragmentation. Sequencing adaptors (blue) are subsequently added to each cDNA fragment and a short sequence is obtained from each cDNA using high-throughput sequencing technology. The resulting sequence reads are aligned with the reference genome or transcriptome, and classified as three types: exonic reads, junction reads and poly(A) end-reads. These three types are used to generate a base-resolution expression profile for each gene. Nat Rev Genet 10(1):57-63 (2009)


RNA-Seq

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    Learn more about available bioinformatics tools and pipelines to analyze RNA sequencing data

    13 hours ago
  • rna-seq

    New search engine for single cell atlases

    14 hours ago
  • rna-seq

    Yale researchers identify tumor reactive immune cells with RNA sequencing to help fight against advanced melanoma

    15 hours ago
  • rna-seq

    New algorithm identifies ‘escaping’ cells in single-cell CRISPR screens

    2 days ago
  • rna-seq

    RNA sequencing brings hope for endangered wild cats

    2 days ago
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    Mim-tRNAseq – A method that accurately measures the abundance and modification status of different tRNAs

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    Uncovering the Anti-Myeloma Resistance Files

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