The Center for Translational and Computational Neuroimmunology at Columbia University in New York, NY (https://www.columbiactcn.org) is seeking two talented post-docs to lead analyses of bulk, single-cell, and spatial transcriptomics data from human brain samples in the context of brain disease. ...
Read More »Scientists using RNA-Seq close in on origins of chronic pain
T System Collaboration Studies Human Nerve Cells for Genes Tied to Neuropathy A new study by researchers at The University of Texas at Dallas, UT MD Anderson Cancer Center, UT Health Science Center at Houston and Baylor College of Medicine ...
Read More »Single-cell RNA-Seq gives scientists unprecedented view of brain development
Detailed measurements of genes in individual brain cells allows scientists to trace specific developmental trajectories in the cerebellum Researchers at St. Jude Children’s Research Hospital have created a massive database of the changes in gene activity of individual cells in ...
Read More »Complex brain circuitry revealed using new single-cell sequencing technology
TGen and Circuit Therapeutics lead discoveries that could help patients with neuro-related conditions such as Parkinson’s and drug addiction...
Read More »New brain cancer coalition announces precision medicine study
Philadelphia Coalition for a Cure (PC4C), a newly launched cooperative clinical diagnostics and research initiative announced that it will collaborate in a study together with Children’s Hospital of Orange County (CHOC) directed to the study and diagnosis of adult and pediatric ...
Read More »Single-cell RNA-Seq supports a role for cancer stem cells in brain tumor growth
Mass. General, Broad Institute team finds strong evidence that cancer stem cells are important drivers of tumors in patients A study analyzing brain tumor genomics on a single-cell level has found evidence that cancer stem cells fuel the growth of ...
Read More »Revolutionary method to map brains at single-neuron resolution successfully demonstrated
MAPseq uses RNA sequencing to rapidly and inexpensively find the diverse destinations of thousands of neurons in a single experiment in a single animal Neuroscientists have published in Neuron the details of a revolutionary new way of mapping the brain ...
Read More »Single nuclei RNA-Seq supplies snapshot of gene expression across brain
from Spectrum.com by Ann Griswold – A new tool provides speedy analysis of gene expression patterns in individual neurons from postmortem brain tissue. Researchers have used the method to compare the genetic signatures of more than 3,000 neurons from distant ...
Read More »Transcriptome Sequencing Links Bipolar Disorder to Unexpected Brain Region
While bipolar disorder is one of the most-studied neurological disorders—the Greeks noticed symptoms of the disease as early as the first century—it’s possible that scientists have overlooked an important part of the brain for its source. Scientists from the Florida ...
Read More »Single-cell RNA sequencing reveals human brain houses diverse populations of neurons
A team of researchers has developed the first scalable method to identify different subtypes of neurons in the human brain. The research lays the groundwork for “mapping” the gene activity in the human brain and could help provide a better ...
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