Tag Archives: broad institute

The scale and capabilities of single-cell RNA-sequencing methods have expanded rapidly in recent years, enabling major discoveries and large-scale cell mapping efforts. However, these methods have not been systematically and comprehensively...

Study finds specific cells in the lungs, nasal passages, and intestines that are more susceptible to infection. Researchers at MIT; the Ragon...

DroNc-Seq — a technology that merges single-nucleus RNA sequencing with microfluidics — brings new scale to gene expression studies in complex tissues. from The Broad Institute by Tom Ulrich –  Last year Broad researchers described a single-nucleus RNA sequencing method called sNuc-Seq. This ...

from Nature by Anna Nowogrodzki – Aviv Regev likes to work at the edge of what is possible. In 2011, the computational biologist was collaborating with molecular geneticist Joshua Levin to test a handful of methods for sequencing RNA. The ...

Join us for the fifth and final GTEx Community Scientific meeting. June 28, 2017 in Rockville, MD. The GTEx Community meeting has been an annual event that is open to the scientific community interested in learning more about the project ...

Researchers from UC San Francisco and the Broad Institute of MIT and Harvard have developed a new method for performing high-throughput functional screening of complex genetic interactions and resulting phenotypes in single cells, which they have dubbed “Perturb-seq.” The findings ...

As part of the process of preparing scRNA-seq libraries, a diverse template is typically amplified by PCR. During amplification, spurious chimeric molecules can be formed between molecules originating in different cells. While several computational and experimental strategies have been suggested ...

Description: The Shalek Lab (http://shaleklab.com, MIT, Broad Institute, and Ragon Institute) in collaboration with the Walker Lab (http://www.ragoninstitute.org/portfolio-item/walker-lab/, Ragon Institute) has an opening for a highly motivated Research Technician to assist in a global profiling of the immune system in acute ...

Specialty: Computational Biology Program: Cancer Genome Analysis Job Description: The Broad Institute of MIT & Harvard is looking to hire an exceptional candidate to join the team leading data production and analyses for the Genotype-Tissue Expression Consortium (commonfund.nih.gov/GTEx and gtexportal.org). The goal of ...

Reporter gene assays are a venerable tool for studying signaling pathways, but they lack the throughput and complexity necessary to contribute to a systems-level understanding of endogenous signaling networks. Researchers from the Broad Institute have devloped a parallel reporter assay, ...