RNA-Seq Blog Transcriptome Research & Industry News
RNA-seq analysis of human breast cancer data
Read More »Tutorial – RNA-seq analysis of human breast cancer data
MULSEA – Mutual enrichment in aggregated ranked lists with applications to gene expression regulation
It is often the case in biological measurement data that results are given as a ranked list of quantities-for example, differential expression (DE) of genes as inferred from microarrays or RNA-seq. Recent years brought considerable progress in statistical tools for ...
Read More »RNA-Seq Identifies New Treatment Target for Prostate Cancer Tumors
Prostate cancer patients have been offered hope after scientists at Newcastle University have identified a new group of molecules that could be targeted to slow tumour growth. A 3-year research project involved the use of an advanced screening technique called ...
Read More »Moon Shots Program APOLLO Project to Perform DNA / RNA-Seq on Serial Biopsies
Biopsies before, during, after therapy and deep molecular analysis seek tumor tricks to target A study that indicates how advanced melanoma responds to an immunotherapy, published in Cancer Discovery, demonstrates a revolutionary approach from The University of Texas MD Anderson ...
Read More »RNA-Seq highlights racial disparities and vitamin D in prostate cancer
The results of clinical studies by investigators at the Medical University of South Carolina (MUSC) and the Ralph H. Johnson VA Medical Center (VAMC), reported in the July 2016 issue of Pharmacogenomics, demonstrate transcriptome-level linkages between racial disparities in circulating ...
Read More »SMC-RNA Challenge launched to identify the best methods for detecting rearrangements in RNA-seq data
An open challenge that merges the efforts of the International Cancer Genome Consortium, The Cancer Genome Atlas, and the NCI Cloud Pilots with Sage Bionetworks and the open science DREAM Challenge community Scientists from around the world have announced a ...
Read More »An Integrated Approach for RNA-seq Data Normalization
DNA copy number alteration is common in many cancers. Studies have shown that insertion or deletion of DNA sequences can directly alter gene expression, and significant correlation exists between DNA copy number and gene expression. Data normalization is a critical ...
Read More »Genomic Expression makes Red Herring “Top 100” for disprupting cancer care with RNA-Seq
Genomic Expression (http://www.genomicexpression.com), first mover in making RNA sequencing actionable in oncology, today announced that it has won the Red Herring Top 100 North America award. The award recognizes leading private companies, celebrating these startups’ innovations and technologies across their ...
Read More »Novel and potentially clinically relevant gene fusions discovered by integrated mate-pair and RNA sequencing
Peripheral T-cell lymphomas (PTCLs) represent a heterogeneous group of T-cell malignancies that generally demonstrate aggressive clinical behavior, often are refractory to standard therapy, and remain significantly understudied. The most common World Health Organization subtype is PTCL, not otherwise specified (NOS), ...
Read More »Single-cell RNA-sequencing Can Resolve Malignant, Non-malignant Heterogeneity
from CancerTherapyAdvisor by Jason Hoffman, PharmD, RPh – CHICAGO —Single-cell RNA-sequencing can resolve the heterogeneity of both malignant and non-malignant tumor components, according to findings presented at the 2016 American Society of Clinical Oncology (ASCO) Annual Meeting. Current profiling technologies provide ...
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