Targeted next-generation sequencing of DNA has become more widely used in the management of patients with lung adenocarcinoma; however, no clear mitogenic driver alteration is found in some cases. Researchers at Memorial Sloan Kettering Cancer...
Read More »A comparison of survival analysis methods for cancer gene expression RNA-Sequencing data
Identifying genetic biomarkers of patient survival remains a major goal of large-scale cancer profiling studies. Using gene expression data to predict the...
Read More »New computational tool enables powerful molecular analysis of biomedical tissue samples
Stanford researchers have developed a computational platform for analyzing the molecular behavior of individual cells in tissue samples,...
Read More »Extremely precise RNA sequencing may improve detection and treatment of advanced brain cancer
In a new study, Yale Cancer Center scientists have demonstrated a powerful method to analyze how tumor cells are altered as they metastasize, or spread, to the brain. The research, published in the journal Cell Reports, may eventually improve early diagnosis and treatment ...
Read More »Comparison of RNA-Seq data alignment and qene expression quantification tools for clinical breast cancer research
The rapid expansion of transcriptomics and affordability of next-generation sequencing (NGS) technologies generate rocketing amounts of gene expression data across biology and medicine, including...
Read More »Wanted – RNA-seq bioinformatics wizard with interest in curing cancer
Location: Beverly, MA Department: Boston Lab Type: Full Time Min. Experience: ExperiencedCompany DNA: Genomic Expression is finding the best drug for the patient and the best patient for the drug by sequencing RNA. Analyzing RNA is able to tell if ...
Read More »Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing
Cancer-associated fibroblasts (CAFs) are a major constituent of the tumor microenvironment, although their origin and roles in shaping disease initiation, progression and treatment response remain unclear...
Read More »Upcoming Webinar – The SG-NEx project: nanopore long-read RNA-sequencing of human cancer cell lines
28 Feb 2019 at 11:00 (GMT -06:00) Jonathan Göke – Senior Research Scientist (PI) Genome Institute of Singapore (A*STAR) The ability of RNA-sequencing to generate a high-dimensional, quantitative readout...
Read More »An enrichment system to facilitate isolation and molecular characterization of single cancer cells
Circulating tumor cells (CTCs) carry valuable biological information. While enumeration of CTCs in peripheral blood is an FDA-approved prognostic indicator of survival in metastatic prostate and other...
Read More »Open source machine learning tool for analysis of RNA-seq data could help choose cancer drugs
The selection of a first-line chemotherapy drug to treat many types of cancer is often a clear-cut decision governed by standard-of-care protocols, but...
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