The majority of the human genome is differentially expressed across a wide dynamic range to produce a spectrum of protein-coding and noncoding RNAs, generating a transcriptome of unexpected scale and complexity. These features present a challenge for gene-expression profiling with ...
Read More »Improved definition of the mouse transcriptome via targeted RNA sequencing
Targeted RNA sequencing (CaptureSeq) uses oligonucleotide probes to capture RNAs for sequencing, providing enriched read coverage, accurate measurement of gene expression, and quantitative expression data. Researchers from the European Bioinformatics Institute applied CaptureSeq to refine transcript annotations in the current ...
Read More »Study Points to Utility of Targeted RNA Sequencing for Low-abundance Transcripts
from GenomeWeb NEW YORK (GenomeWeb) – A team led by researchers from Australia’s Garvan Institute of Medical Research this week reported new data demonstrating the superiority of a targeted RNA sequencing method called “capture sequencing” (CaptureSeq) over standard RNA sequencing ...
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