Tag Archives: cell lineage

Our body consists of numerous cells that are functioning continuously to keep us alive. Even though the cells in different organs contain almost similar DNA, they can perform different functions. While the cells perform different functions, their...

Several recent studies focus on the inference of developmental and response trajectories from single cell RNA-Seq (scRNA-Seq) data. A number of computational methods, often referred to as...

Scientists are finding that they can understand organ function (and dysfunction in the case of disease) better if they know where the cells that make up these organs came from. New single-cell technologies allow all cell states within a differentiating ...

A new algorithm created at A*STAR allows scientists to track the trajectories of different cell lineages on the basis of their gene activity at the individual cell level. The tool, dubbed Mpath, should help reveal new insights into disease states ...

Mouse studies have been instrumental in forming our current understanding of early cell-lineage decisions; however, similar insights into the early human development are severely limited. Here, researchers from the Karolinska Institutet present a comprehensive transcriptional map of human embryo development, ...