Researchers from Stefan Kubicek's and Christoph Bock’s groups, at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna, have developed a method to...
Read More »CRISPR meets single-cell RNA sequencing in new screening method
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences Genome editing using CRISPR/Cas9 “gene scissors” is a powerful tool for biological discovery and for identifying novel drug targets. In pooled CRISPR screens, a large number of cells ...
Read More »Allelome.PRO – a pipeline to define allele-specific genomic features from high-throughput sequencing data
Detecting allelic biases from high-throughput sequencing data requires an approach that maximises sensitivity while minimizing false positives. Here, researchers from the CeMM Research Center for Molecular Medicine present Allelome.PRO, an automated user-friendly bioinformatics pipeline, which uses high-throughput sequencing data from ...
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