UNC Lineberger is a major site of NCI's Cancer Genome Atlas research with an emphasis on RNA sequencing and combined bioinformatic analysis of multiple omics data. In addition, UNC Lineberger supports its longstanding UNC Breast Cancer SPORE grant that has...
Read More »A novel multi-alignment pipeline for high-throughput sequencing data
Mapping reads to a reference sequence is a common step when analyzing allele effects in high-throughput sequencing data. The choice of reference is critical because its effect on quantitative sequence analysis is non-negligible. Recent studies suggest aligning to a single ...
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