Small RNA-seq – The RNA 5′-end adapter ligation problem and how to circumvent it

May 16, 2019 Leave a comment 2,488 Views

The preparation of small RNA cDNA sequencing libraries depends on the unbiased ligation of adapters to the RNA ends. Small RNA with 5' recessed ends are poor substrates for enzymatic adapter ligation, but this 5' adapter ligation problem can...

RNA-Seq Blog Transcriptome Research & Industry News

Tag Archives: CircLigase

Small RNA-seq – The RNA 5′-end adapter ligation problem and how to circumvent it

A single-cell resolution atlas of human adenomas and serrated polyps sets framework for precision surveillance of colorectal cancer

Analysis of small RNA sequencing data in plants

Researchers combine single cell sequencing data with spatial information to create unprecedented cellular maps of tissues

MGcount – a total RNA-seq quantification tool to address multi-mapping and multi-overlapping alignments ambiguity in non-coding transcripts

Zero-preserving imputation of single-cell RNA-seq data

Featured RNA-Seq Job – Computational Scientist

Veranome Biosystems and Cold Spring Harbor Laboratory Enter Collaboration and Licensing Agreement to Develop Advanced In-Situ Sequencing Technologies