Tag Archives: circular RNA

PcircRNA_finder – circRNA prediction in plants

rna-seq

Recent studies reveal an important role of non-coding circular RNA (circRNA) in the control of cellular processes. Because of differences in the organization of plant and mammal genomes, the sensitivity and accuracy of circRNA prediction programs using algorithms developed for ...

Read More »

CIRI – de novo circular RNA identification

rna-seq

Recent studies reveal that circular RNAs (circRNAs) are a novel class of abundant, stable and ubiquitous noncoding RNA molecules in animals. A comprehensive detection of circRNAs from high-throughput transcriptome data is an initial and crucial step to study their biogenesis ...

Read More »

Scientists discover how disruptive genetic RNA is made

rna-seq

Israeli-led research finds circular RNA puts brakes on gene expression, could cause degenerative disease from Times of Israeli by Andrew Tobin An Israeli-led research team has discovered how a mysterious circular type of genetic molecule is produced, and that might ...

Read More »

Cofactor Genomics Awarded NIH Grant to Develop a Circular RNA Enrichment Kit and Reference Profile

rna-seq

August 2014, Cofactor Genomics has been awarded a grant by the National Institute of Mental Health (NIMH), an institute of the NIH, to develop a standardized enrichment kit and define the normal reference profile for circular RNAs (circRNA) in the nervous ...

Read More »

Detecting and characterizing circular RNAs

rna-seq

Circular RNA transcripts were first identified in the early 1990s but knowledge of these species has remained limited, as their study through traditional methods of RNA analysis has been difficult. Now, novel bioinformatic approaches coupled with biochemical enrichment strategies and ...

Read More »