Biases during read mapping can be avoided by mapping reads to two alternative genomes

May 23, 2014 Leave a comment 4,527 Views

Genetic variation in cis-regulatory elements is an important cause of variation in gene expression. Cis-regulatory variation can be detected by using high-throughput RNA sequencing (RNA-seq) to identify differences in the expression of the two alleles of a gene. This requires ...

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Biases during read mapping can be avoided by mapping reads to two alternative genomes

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