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RNA cleavage by some endoribonucleases and self-cleaving ribozymes produces RNA fragments with 5′-hydroxyl (5′-OH) and 2′,3′-cyclic phosphate termini. To identify 5′-OH RNA fragments produced by these cleavage events, researchers from the University of Colorado School of Medicine exploited the unique ligation ...
Read More »Global analysis of RNA cleavage by 5′-hydroxyl RNA sequencing
