Tag Archives: CNRS

Study with Human Cell Atlas could help understand transmission of the virusTwo specific cell types in the nose have been identified as likely initial infection points for COVID-19 coronavirus. Scientists discovered that goblet and ciliated cells...

Biosensors are biological molecules able to detect and report the presence of a target molecule by the emission of a signal. Nucleic acids are particularly appealing for the design of such molecule since their...

The field of small RNA is one of the most investigated research areas since they were shown to regulate transposable elements and gene...

Despite its apparent simplicity – a tube-like body topped with tentacles –, the sea anemone is actually a highly complex creature. Scientists from the Institut Pasteur, in collaboration with the CNRS, have just discovered over a hundred different cell types in ...

Polyadenylation is thought to be involved in the degradation and quality control of bacterial RNAs but relatively few examples have been investigated. Researchers at the CNRS used a combination of 5΄-tagRACE and RNA-seq to analyze the total RNA content from ...

Whole transcriptome sequencing (RNA-seq) has become a standard for cataloguing and monitoring RNA populations. One of the main bottlenecks, however, is to correctly identify the different classes of RNAs among the plethora of reconstructed transcripts, particularly those that will be ...

Over recent decades, substantial efforts have been made to understand the interactions between host genomes and transposable elements (TEs). The impact of TEs on the regulation of host genes is well known, with TEs acting as platforms of regulatory sequences. ...

Numerous statistical pipelines are now available for the differential analysis of gene expression measured with RNA-sequencing technology. Most of them are based on similar statistical frameworks after normalization, differing primarily in the choice of data distribution, mean and variance estimation ...

The development of High Throughput Sequencing (HTS) for RNA profiling (RNA-seq) has shed light on the diversity of transcriptomes. While RNA-seq is becoming a de facto standard for monitoring the population of expressed transcripts in a given condition at a ...

Researchers from CNRS/Université Lyon have developed a probabilistic framework to infer autosomal and sex-linked genes from RNA-seq data of a cross for any sex chromosome type (XY, ZW, UV). Sex chromosomes (especially the non-recombining and repeat-dense Y, W, U and ...