Tag Archives: Cold Spring Harbor Laboratory

Many tools are available for RNA-seq alignment and expression quantification, with comparative value being hard to establish. Benchmarking assessments often highlight methods' good performance, but are focused on either model data or fail to explain...

Envisagenics is the developer of SpliceCore, software that analyzes RNA sequencing (RNA-seq) data to accelerate RNA therapeutics discovery using innovative machine learning to identify new...

Humans, chimps and monkeys have strikingly similar genomes. This data helps us understand differences across these primate species. It displays information

Breakout Labs, the Thiel Foundation’s seed-stage fund for deep technology companies, announced its latest four investments, each propelling radical science and technology to improve human health. The new awards bring the total number of companies backed by Breakout Labs to ...

The spatial information associated with gene expression is important for elucidating the context-dependent transcriptional regulation during development. Recently, high-resolution sampling approaches, such as RNA tomography or single-cell RNA-seq combined with fluorescence in situ hybridization (FISH), have provided indirect ways to ...

Cold Spring Harbor, NY — There is staggering diversity in the number of flowers produced by each of the 2,800 or so species of plants in the nightshade family, which includes economically important crops such as tomatoes, peppers, and potatoes. ...

Improvements in maize breeding are required to feed a growing population and will depend on a more complete understanding of global gene expression in the plant. In a new publication from Cold Spring Harbor Laboratory (CSHL), scientists produced the largest ...

Co-expression networks have been a useful tool for functional genomics, providing important clues about the cellular and biochemical mechanisms that are active in normal and disease processes. However, co-expression analysis is often treated as a black box with results being ...

In addition to detecting novel transcripts and higher dynamic range, a principal claim for RNA-sequencing has been greater replicability, typically measured in sample-sample correlations of gene expression levels. Through a re-analysis of ENCODE data, researchers at Cold Spring Harbor Laboratory ...

Designing RNA-Seq experiments, Eric Antoniou, Ph.D. – Dr Antoniou, Research Investigator, Cancer Center Genomics, Cold Spring Harbor Laboratory gives an overview for how to design RNA-Seq experiments.