Bayer today announced the launch of Test4TRK™ program in collaboration with NeoGenomics, Inc. to offer genomic cancer testing for NTRK gene fusions at no cost for patients with RAI-refractory (RAI-R) differentiated thyroid carcinoma (DTC) and metastatic...
Read More »First Peggy Prescott Award will be used for scRNA-Seq in colorectal cancer research
Fellowship Funded by Dallas Cowboys QB and SU2C Ambassador Dak Prescott in Honor of His Late Mother Who Died of the Disease Stand Up To...
Read More »Single cell RNA-Seq technology and organoids reveal every bowel tumour and bowel cancer cell have unique genetic fingerprints
Study could help researchers target cancer-specific processes for cancer prevention or to develop treatments New research on bowel cancer has shown that every tumour is different, and that every cell within the tumour is also genetically unique. In the first ...
Read More »Eliminating platform-based bias
Molecular subtypes of cancers and autoimmune disease, defined by transcriptomic profiling, have provided insight into disease pathogenesis, molecular heterogeneity, and therapeutic responses. However, technical biases inherent to different gene...
Read More »A RNA-Sequencing approach for the identification of novel long non-coding RNA biomarkers in colorectal cancer
Long non-coding RNAs (lncRNAs) have been implicated in human pathology, however, their role in colorectal carcinogenesis have not been fully elucidated. In the current study, researchers from Baylor...
Read More »RNA-Seq provides first evidence of chemopreventive effect of a low dose combination of aspirin and Curcumin C3 Complex
In an extensive efficacy and mechanistic study using transcriptomic analysis using RNA-seq published in the leading journal Biochemical Pharmacology, researchers provided the first evidence of chemopreventive effect of a low dose combination of aspirin and Sabinsa’s Curcumin C3 Complex®. Colorectal cancer ...
Read More »Splicify – a proteogenomic pipeline to detect differentially expressed protein isoforms based on integrating RNA-Seq and Mass Spec data
Proteogenomics, i.e. comprehensive integration of genomics and proteomics data, is a powerful approach identifying novel protein biomarkers. This is especially the case for proteins that differ structurally between disease and control conditions. As tumor development is associated with aberrant splicing, ...
Read More »Researchers identify recurrent sources of technical variability in RNA profiling
Histopathology-based staging of colorectal cancer (CRC) has utility in assessing the prognosis of patient subtypes, but as yet cannot accurately predict individual patient’s treatment response. Transcriptomics approaches, using array based or next generation sequencing (NGS) platforms, of formalin fixed paraffin ...
Read More »Single-cell RNA-Seq reveals subtypes of colorectal tumors
Combining single-cell genomics and computational techniques, a research team including Paul Robson, Ph.D., director of single-cell biology at The Jackson Laboratory (JAX), has defined cell-type composition of cancerous cells from 11 colorectal tumors, as well as adjacent noncancerous cells, a ...
Read More »Upcoming Webinar – RNA-Seq in Colorectal Cancer Impacting Future Treatments
Date: Wednesday, October 19, 2016 Time: 11am EDT (NA) / 4pm BST (UK) / 5pm CEST (EU-Central) Duration: 60 minutes Featured Speaker: Enzo Medico, MD, PhD, Associate Professor, University of Torino, School of Medicine, Candiolo Cancer Institute In this webinar, ...
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