Pharmacological and functional genomic screens play an essential role in the discovery and characterization of therapeutic targets and associated pharmacological inhibitors. Although these screens affect thousands of gene products, the typical readout is based on low complexity rather than genome-wide ...
Read More »Featured RNA-Seq Job – Associate Research Scientist
Requisition Number: 0007907 Field(s) of Specialization: Position Title: Associate Research Scientist Department: 7574- JSB C2B2 Department Number: 757400X Location: Medical Center Summary Description Columbia University is looking for a highly motivated scientist to lead the analysis of large-scale genome and ...
Read More »Post-doc position available – single cell RNA-Seq
A Postdoctoral position is available in the laboratory of Peter Sims at Columbia University Medical Center in the Dept. of Systems Biology. The Sims Lab develops and applies new tools for genome- and transcriptome-wide analysis of individual cells using cutting-edge ...
Read More »Topological RNA-Seq provides roadmap for cell development
Topological representation of four cellular populations during motor neuron differentiation. (Image credit: Rabadan lab/Columbia University Medical Cente Researchers at Columbia University Medical Center have created a new tool to describe the many possible ways in which a cell may develop. ...
Read More »RNA-seq is clinically impactful
Molecular characterization has the potential to advance the management of pediatric cancer and high-risk hematologic disease. The clinical integration of genome sequencing into standard clinical practice has been limited and the potential utility of genome sequencing to identify clinically impactful ...
Read More »An Automated Microwell Platform for Large-Scale Single Cell RNA-Seq
Recent developments have enabled rapid, inexpensive RNA sequencing of thousands of individual cells from a single specimen, raising the possibility of unbiased and comprehensive expression profiling from complex tissues. Microwell arrays are a particularly attractive microfluidic platform for single cell ...
Read More »A new platform for single-cell imaging and sequencing
Researchers from Columbia University Medical Center have developed an important technical advance that marries the simplicity of microwells and the early technique of barcoding of droplets with the parallelizability of microfluidics to enable many single cells from multiple different samples ...
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