Tag Archives: Cornell University

The study of pre-mRNA splicing has been greatly aided by the advent of RNA sequencing (RNA-seq), which enables the genome-wide detection of discrete splice isoforms. Quantification of these splice isoforms requires analysis of splicing informative...

Next-Generation Sequencing has made available substantial amounts of large-scale Omics data, providing unprecedented opportunities to understand complex biological systems. Specifically, the value of RNA-Sequencing (RNA-Seq) data has...

Droplet microfluidics has revolutionized single-cell RNA sequencing, offering a low-cost, high-throughput method for single-cell genomics. However, this method has been limited in its ability to capture complete RNA transcription information. Researchers at Cornell – led by Iwijn De Vlaminck...

Post-transcriptional RNA processing is a core mechanism of gene expression control in cell stress response. The poly(A) tail influences mRNA translation and stability, but it is unclear whether...

Few studies about bamboo naturally occurring mutants have been reported so far. Using an integrated anatomy, mathematics and genomics approach, A team led by researchers at Cornell University systematically characterized the cellular and molecular basis underlying the abnormal internode development ...

Job #298421738 Cornell University Ithaca, NY Title: Postdoctoral Associate for Statistical Genetics and Genomics in Oat, Section of Plant Breeding and Genetics, School of Integrative Plant Science, CALS, Cornell University Location: Ithaca Summary A postdoctoral associate position is available to ...

RNA-seq is increasingly used to study gene expression of various organisms. While it provides a great opportunity to explore genome-scale transcriptional patterns with tremendous depth, it comes with prohibitive costs. Establishing a minimal sequencing depth for required accuracy will guide ...

De novo assembled transcriptomes, in combination with RNA-Seq, are powerful tools to explore gene sequence and expression level in organisms without reference genomes. Investigators must first choose which high throughput sequencing platforms will provide data most suitable for their experimental ...

from the Cornell Chronicle by Carly Hodes Cornell scientists exploring the road from genes to proteins can access a new research service that helps map some of its more mysterious turns. The university has established the RNA Sequencing Core (RSC) ...

Genomic imprinting is manifested as differential allelic expression (DAE) depending on the parent-of-origin. The most direct way to identify imprinted genes is to directly score the DAE in a context where one can identify which parent transmitted each allele. Because ...