Due to fast transmission and various circulating SARS-CoV-2 variants, a significant increase of coronavirus 2019 infection cases with acute respiratory symptoms has prompted worries about the...
Read More »A LAMP sequencing approach for high-throughput co-detection of SARS-CoV-2 and influenza virus in human saliva
The COVID-19 pandemic has created an urgent need for rapid, effective, and low-cost SARS-CoV-2 diagnostic testing. Researchers at the University of Pennsylvania Perelman School of Medicine describe...
Read More »RNA-Seq data pipeline quickly identifies SARS-CoV-2 therapeutics
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the etiological agent of coronavirus disease-2019 (COVID-19), is a novel Betacoronavirus that was first reported in Wuhan, China in Dec...
Read More »Analysis workflow for publicly available RNA-sequencing datasets
Differential gene expression analysis is widely used to study changes in gene expression profiles between two or more groups of samples (e.g., physiological versus pathological conditions...
Read More »DeepSARS – simultaneous diagnostic detection and genomic surveillance of SARS-CoV-2
The continued spread of SARS-CoV-2 and emergence of new variants with higher transmission rates and/or partial resistance to vaccines has...
Read More »Comprehensive investigation of COVID-19 RNA-sequencing dataset
The goal of this study is to reveal the hub genes and molecular mechanisms of the coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS) based on the genome-wide RNA...
Read More »Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’
The in vivo phenotypic profile of T cells reactive to severe acute respiratory syndrome (SARS)-CoV-2 antigens remains poorly understood. Conventional methods to detect antigen-reactive T cells require in...
Read More »Findings may help close door on COVID-19
Researchers at Vanderbilt University Medical Center (VUMC) and the University of Texas Medical Branch (UTMB) at Galveston have discovered what may be the Achilles’ heel of the coronavirus, a finding that may help close the door on COVID-19 and possibly ...
Read More »Twist Bioscience to offer synthetic RNA control for UK variant strain of SARS-CoV-2
Twist Bioscience Corporation, a company enabling customers to succeed through its offering of high-quality synthetic DNA using its silicon platform, today announced plans to offer a new synthetic RNA control that includes the new variant of SARS-CoV-2...
Read More »New app enables RNA sequencing data analysis on your smartphone
A team led by Garvan’s Dr Ira Deveson developed the app ‘Genopo’ that can analyse the coronavirus genome on a portable Android device. A new mobile app has made it possible to analyse the genome of...
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