For the first time, scientists at the Federal University of São Paulo (UNIFESP) in Brazil have shown that infection by SARS-CoV-2, the virus that causes COVID-19, changes the functioning of host cell RNA. They arrived at this conclusion by analyzing ...
Read More »New type of RNA discovered
Novel immunostimulatory dsRNAs activate antiviral responses against multiple pandemic viruses in mouse and human organ chip models. RNA is often described as the single-stranded cousin of DNA, the double-stranded molecule that makes up the genomes of all living organisms. Many ...
Read More »RNA sequencing reveals why people with COPD are more susceptible to COVID-19
Researchers from the Centenary Institute and the University of Technology Sydney have published the first study showing why people with chronic...
Read More »Long-term perturbation of the transcriptome months after SARS-CoV-2 infection
Scientists in Australia have published a multi-omics analysis of immune responses in blood at a transcriptional, cellular, and serological level at 12, 16, and 24 weeks post-infection (wpi) in 69 patients recovering from mild, moderate, severe, or critical COVID-19 in comparison ...
Read More »Sequencing an important part of National COVID-19 Preparedness Plan
The Administration will work with Congress to secure the necessary funding to improve our data collection, sequencing, and wastewater surveillance capabilities to immediately identify and detect new and emerging variants; and strengthen pandemic...
Read More »What is going on at the single-cell level in the first days of SARS-CoV-2 infection in the lungs?
Sequencing more than 170,000 single cells from animal models have provided exceptionally detailed insight into the early immune response to SARS...
Read More »Whole blood RNA sequencing approach to identifying RNA biomarkers for COVID-19
George Washington University researchers have developed a blood test that quickly detects if someone has COVID-19 and predicts how severely...
Read More »SwabSeq – Scalable, Sensitive and Fast COVID-19 Testing
The UCLA–developed diagnostic technology has helped keep the university and other large client organizations operational during the pandemic. After much of Los Angeles went dark in the spring of 2020
Read More »Standard transcriptomic analyses cannot fully capture the molecular mechanisms underlying disease pathophysiology and outcomes
Researchers at Cincinnati Children’s Hospital Medical Center present a computational heterogeneous data integration and mining protocol that combines transcriptional signatures from multiple model systems...
Read More »CellHeap – a workflow for optimizing COVID-19 single-cell RNA-Seq data processing
Currently, several hundreds of Terabytes of COVID-19 single-cell RNA-seq (scRNA-seq) data are available in public repositories. This data refers...
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