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Tag Archives: Curriculum

A new University of Pennsylvania effort is bringing RNA sequencing into high school classrooms through a free online resource

December 7, 2016 Leave a comment 3,301 Views

rna-seq

The goal is to make it easier for science teachers to incorporate the latest advances in science into their curricula. The initiative, Discovering the Genome, was spearheaded by Kristin Field, director of programs at Penn’s Nano/Bio Interface Center, and Junhyong ...

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Detection and application of novel SSR markers from transcriptome data for Astronium fraxinifolium Schott, a threatened Brazilian tree species
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What is RNA-Seq?

long RNAs are first converted into a library of cDNA fragments through either RNA fragmentation or DNA fragmentation. Sequencing adaptors (blue) are subsequently added to each cDNA fragment and a short sequence is obtained from each cDNA using high-throughput sequencing technology. The resulting sequence reads are aligned with the reference genome or transcriptome, and classified as three types: exonic reads, junction reads and poly(A) end-reads. These three types are used to generate a base-resolution expression profile for each gene. Nat Rev Genet 10(1):57-63 (2009)


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    scGNN – a novel graph neural network framework for single-cell RNA-Seq analyses

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