LaSSO, a strategy for genome-wide mapping of intronic lariats and branch-points using RNA-Seq

April 10, 2014 Leave a comment 11,559 Views

Both canonical and alternative splicing of RNAs is governed by intronic sequence elements and produces transient lariat structures fastened by branch-points within introns. To map precisely the location of branch-points on a genomic scale, researchers at University College London developed ...

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