Mutual – heuristic pairwise alignment of de Bruijn graphs to facilitate simultaneous transcript discovery

November 11, 2015 Leave a comment 3,080 Views

The advance of high-throughput sequencing has made it possible to obtain new transcriptomes and study splicing mechanisms in non-model organisms. In these studies, there is often a need to investigate the transcriptomes of two related organisms at the same time ...

Kpath ‐ statistical reference-based compression for short reads

February 6, 2015 Leave a comment 3,329 Views

Storing, transmitting, and archiving data produced by next generation sequencing is a significant computational burden. New compression techniques tailored to short-read sequence data are needed. Researchers from Carnegie Mellon University and Stony Brook University have devloped an approach to compression ...

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Tag Archives: de Bruijn graphs

Mutual – heuristic pairwise alignment of de Bruijn graphs to facilitate simultaneous transcript discovery

Kpath ‐ statistical reference-based compression for short reads

ac4C-seq – quantitative nucleotide resolution profiling of RNA cytidine acetylation

Trips-Viz: an environment for the analysis of public and user-generated ribosome profiling data

IsoSeek – unbiased and UMI-informed sequencing of cell-free miRNAs at single-nucleotide resolution

Cell-level metadata are indispensable for documenting single-cell RNA sequencing datasets

Strategies for detecting and identifying biological signals amidst the variation commonly found in RNA sequencing data

Researchers use single-cell RNA sequencing to create critical new resource to boost coral reef conservation efforts

Sanity – bayesian inference of gene expression states from single-cell RNA-seq data