Mutual – heuristic pairwise alignment of de Bruijn graphs to facilitate simultaneous transcript discovery

November 11, 2015 Leave a comment 3,043 Views

The advance of high-throughput sequencing has made it possible to obtain new transcriptomes and study splicing mechanisms in non-model organisms. In these studies, there is often a need to investigate the transcriptomes of two related organisms at the same time ...

Kpath ‐ statistical reference-based compression for short reads

February 6, 2015 Leave a comment 3,140 Views

Storing, transmitting, and archiving data produced by next generation sequencing is a significant computational burden. New compression techniques tailored to short-read sequence data are needed. Researchers from Carnegie Mellon University and Stony Brook University have devloped an approach to compression ...

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Tag Archives: de Bruijn graphs

Mutual – heuristic pairwise alignment of de Bruijn graphs to facilitate simultaneous transcript discovery

Kpath ‐ statistical reference-based compression for short reads

Mim-tRNAseq – A method that accurately measures the abundance and modification status of different tRNAs

Uncovering the Anti-Myeloma Resistance Files

Long term and short-term effects of RNA fixation on Single Cell RNA Sequencing

Single cell RNA sequencing opens new avenues for eradicating leukaemia at its source

2passtools: two-pass alignment using machine-learning-filtered splice junctions increases the accuracy of intron detection in long-read RNA sequencing

scRNA-Seq reveals a new type of bone cell that may uncover therapeutic targets for a range of skeletal diseases

DEBKS – a tool to detect differentially expressed circular RNA