Differential expression analysis of RNA sequencing (RNA-seq) data typically relies on reconstructing transcripts or counting reads that overlap known gene structures. Previously, researchers at Johns Hopkins Bloomberg School of Public Health introduced an intermediate approach called differentially expressed region (DER) finder ...
Read More »Derfinder – Differential expression analysis of RNA-seq data at single-base resolution
RNA-sequencing (RNA-seq) is a flexible technology for measuring genome-wide expression that is rapidly replacing microarrays as costs become comparable. Current differential expression analysis methods for RNA-seq data fall into two broad classes: (1) methods that quantify expression within the boundaries ...
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