The long-standing enigma of why so many patients suffering with high blood pressure (known as hypertension) also have diabetes (high blood sugar)
Read More »On Demand Webinar – Leveraging 3’ RNA-seq to uncover the link between arsenic exposure and diabetes
Advances in diabetes research facilitated by QIAseq UPX 3′ Transcriptome technology Chronic exposure to environmental arsenic is associated with several diseases, including diabetes mellitus. Join our live...
Read More »An RNA-Seq based approach to identify extracellular vesicle mediated cell-to-cell communication
Exosomes and other extracellular vesicles (EVs) have emerged as an important mechanism of cell-to-cell communication. However, previous studies either did not fully resolve what genetic materials were...
Read More »RNA-Seq brings new molecular insights into diabetes risk
Nestlé Institute of Health Sciences (NIHS) researchers have taken another step forward in understanding the variability in glycaemic improvements following weight loss in overweight and obese people, and why the risk of developing diabetes varies from one individual to the ...
Read More »Single-cell analyses promise insights into pancreatic cell function, diabetes
It’s well known that pancreatic islets of Langerhans contain cells that secrete hormones vital to maintaining glucose homeostasis, including insulin. But the cells comprising the islets are of different types and perform different, complementary functions. Understanding their discrete roles in ...
Read More »RNA-Seq data reveal how obesity causes disease in organs distant from those where fat accumulates
Barcelona, Spain: Obesity is on the rise throughout the world, and in some developed countries two-third of the adult population is either overweight or obese. This brings with it an increased risk of serious conditions such as heart disease, stroke, ...
Read More »Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes
Highlights Defined open chromatin regions in sorted human α- and β-cells using ATAC-seq. Detected type 2 diabetes-associated risk loci in human α- and β-cell open chromatin. Classified human α- and β-cell-specific transcripts using mRNA-seq. Discovered novel ...
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