Tag Archives: differential transcript usage

Detection of differential transcript usage (DTU) from RNA-seq data is an important bioinformatic analysis that complements differential gene expression analysis. Researchers at the University of North Carolina at Chapel Hill have developed a simple workflow...

The aim of may RNA-seq studies is differential expression (DE) analysis between conditions of interest. The decreasing cost of sequencing has allowed for complex experimental designs, involving many samples over multiple conditions. Additionally, novel computational methods allow accurate estimation of transcript ...

RNA-seq has been a boon to the quantitative analysis of transcriptomes. A notable application is the detection of changes in transcript usage between experimental conditions. For example, discovery of pathological alternative splicing may allow the development of new treatments or ...