RNA-Seq reveals DNA base editing induces substantial off-target RNA mutations

June 13, 2019 Leave a comment 1,821 Views

DNA base-editing methods have enabled direct point mutation correction in genomic DNA without generating any double-strand breaks (DSBs), but the potential off-target effects have limited the application of these methods. Adeno-associated viruses (AAV)...

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RNA-Seq reveals DNA base editing induces substantial off-target RNA mutations

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