Tag Archives: drop-seq

Taming the transcriptome with RNA-Seq

rna-seq

There’s a new RNA-seq in town. Although the old RNA-seq administered a certain rough justice, profiling RNA species well enough to support a relatively crude conception of the transcriptome, the new RNA-seq is more refined...

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Correcting droplet-based single-cell RNA-seq experiments

rna-seq

Single-cell RNA-seq protocols provide powerful means for examining the gamut of cell types and transcriptional states that comprise complex biological tissues. Recently-developed approaches based on droplet microfluidics, such as inDrop or Drop-seq, use massively multiplexed barcoding to enable simultaneous measurements ...

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Comparative analysis of single-cell RNA-sequencing methods

rna-seq

Single-cell mRNA sequencing (scRNA-seq) allows to profile heterogeneous cell populations, offering exciting possibilities to tackle a variety of biological and medical questions. A range of methods has been recently developed, making it necessary to systematically compare their sensitivity, accuracy, precision ...

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