RNA-related applications of the next-generation sequencing (NGS) technologies require context-specific interpretations: e.g., sequence mismatches may indicate sites of RNA editing, or uneven read coverage often points to mature form of microRNA. Existing visualization tools traditionally show RNA molecules in two ...
Read More »GRIT – Genome-guided transcript assembly by integrative analysis of RNA sequence data
The identification of full length transcripts entirely from short-read RNA sequencing data (RNA-seq) remains a challenge in the annotation of genomes. Here researchers from the University of California at Berkeley describe an automated pipeline for genome annotation that integrates RNA-seq ...
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