Novel immunostimulatory dsRNAs activate antiviral responses against multiple pandemic viruses in mouse and human organ chip models. RNA is often described as the single-stranded cousin of DNA, the double-stranded molecule that makes up the genomes of all living organisms. Many ...
Read More »Next-generation sequencing of dsRNA is greatly improved by treatment with the inexpensive denaturing reagent DMSO
dsRNA is the genetic material of important viruses and a key component of RNA interference-based immunity in eukaryotes. Previous studies have noted difficulties in determining the sequence of dsRNA...
Read More »Genome-wide profiling of the C. elegans dsRNAome
Recent studies hint that endogenous dsRNA plays an unexpected role in cellular signaling. However, a complete understanding of endogenous dsRNA signaling is hindered by an incomplete annotation of dsRNA-producing genes. To identify dsRNAs expressed in Caenorhabditis elegans, researchers at the ...
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