Tag Archives: EMASE

Allele-specific expression (ASE) refers to the differential abundance of the allelic copies of a transcript. RNA sequencing (RNA-Seq) can provide quantitative estimates of ASE for genes with transcribed polymorphisms. When short-read sequences are aligned to a diploid transcriptome, readmapping ambiguities ...

EMASE is a software program written in Python to quantify allele-specific expression and gene expression simultaneously from RNA-seq data. EMASE takes in the diploid transcriptome alignment BAM file and GTF file as inputs and estimates expression abundance for each isoforms ...

Narayanan Raghupathy, Ph.D., The Jackson Laboratory April 22, 2014 | 4 p.m. Kinne Library, Morris Building Direct RNA sequencing of genes with polymorphisms can provide quantitative estimates of maternal and paternal alleles’ expression, not just the total gene expression. Narayanan ...