We are seeking to recruit a new member to our team at the University of Cambridge to contribute to the FlyBase Drosophila database. If you are looking for a fulfilling, fly-related career away from the bench, and enjoy the challenge of organizing complex...
Read More »Researchers use single-cell sequencing to understand how cells age
Researchers from the European Bioinformatics Institute (EMBL-EBI), University of Cambridge, the Wellcome Trust Sanger Institute and the Cancer Research UK-Cambridge Institute (CRUK-CI) have shed light on a long-standing debate about why the immune system weakens with age. Their findings, published ...
Read More »Classification of low quality cells from single-cell RNA-seq data
Single-cell RNA sequencing (scRNA-seq) has broad applications across biomedical research. One of the key challenges is to ensure that only single, live cells are included in downstream analysis, as the inclusion of compromised cells inevitably affects data interpretation. Here, researchers ...
Read More »>80% of stochastic allele-specific expression due to single-cell RNA-seq technical noise
Single-cell RNA-sequencing (scRNA-seq) facilitates identification of new cell types and gene regulatory networks as well as dissection of the kinetics of gene expression and patterns of allele-specific expression. However, to facilitate such analyses, separating biological variability from the high level ...
Read More »Making Single-Cell Biology Work
New Collaboration Between EMBL-EBI, the Wellcome Trust Sanger Institute and Fluidigm Keeps Research and Technology on the Cutting-Edge of Single-Cell Genomics December 17, 2014 06:24 AM Eastern Standard Time SOUTH SAN FRANCISCO, Calif. & HINXTON, U.K.–(BUSINESS WIRE)–A formal collaboration was ...
Read More »RNAcentral 1.0 provides a single access point to non-coding RNA data, vastly improving research into gene products
RNAcentral, the first unified resource for all types of non-coding RNA data, has been launched today by the RNAcentral Consortium. It aggregates information from a federation of expert databases, and provides tools for easy browsing. The initial release of RNAcentral ...
Read More »iRAP – an integrated RNA-seq Analysis Pipeline
RNA-sequencing (RNA-Seq) has become the technology of choice for whole-transcriptome profiling. However, processing the millions of sequence reads generated requires considerable bioinformatics skills and computational resources. At each step of the processing pipeline many tools are available, each with specific ...
Read More »Upcoming Workshop – RNA-Seq and ChiP-Seq Data Analysis
Venue: European Bioinformatics Institute, CB10 1SD, United Kingdom See map: Google Maps Date: Wednesday, July 9, 2014 – Thursday, July 10, 2014 Organizers: Gabriella Rustici , Cambridge University, UK Admin support: Rebecca Greenhaff , EMBL-EBI, UK Registration Opens Date: Tuesday, May 20, 2014 ...
Read More »Differential expression analysis for sequencing count data
by Simon Anders at EMBL-EBI
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