Tag Archives: epigenetics

One commonly performed bioinformatics task is to infer functional regulation of transcription factors by observing differential expression under a knockout, and integrating DNA binding information of that...

Researchers find some neurons in the autistic brain preferentially express the copy of a gene inherited from one parent over the other. Many researchers have assumed that most cells express both copies of a gene equally. Studies in cultured cells ...

In 2004, oncologist Gideon Rechavi at Tel Aviv University in Israel and his colleagues compared all the human genomic DNA sequences then available with their corresponding messenger RNAs — the molecules that carry the information needed to make a protein ...

from Genetic Engineering News by Jeffrey S. Buguliskis, Ph.D. The Use of RNA-Seq Has Enormous Applicability toward the Development of Clinical Diagnostics DNA→RNA→Protein. This flow of genetic information has been the framework of modern biology since it was first enunciated ...

Highlights    Defined open chromatin regions in sorted human α- and β-cells using ATAC-seq.    Detected type 2 diabetes-associated risk loci in human α- and β-cell open chromatin.    Classified human α- and β-cell-specific transcripts using mRNA-seq.    Discovered novel ...

Advances in next-generation sequencing platforms have reshaped the landscape of functional genomic and epigenomic research as well as human genetics studies. Annotation of noncoding regions in the genome with genomic and epigenomic data has facilitated the generation of new, testable ...

from NatureJobs Employer: Johns Hopkins University Location: Posted: June 28, 2014 Expires: August 22, 2014 The laboratory of Human Environmental Epigenomes of Dr. Zhibin Wang at Johns Hopkins University is looking for one or two postdoctoral fellow(s) to join a ...

Despite the prevalent studies of DNA/Chromatin related epigenetics, such as, histone modifications and DNA methylation, RNA epigenetics has not drawn deserved attention until a new affinity-based sequencing approach MeRIP-Seq was developed and applied to survey the global mRNA N6-methyladenosine (m6A) ...

from Zone in with Zon by Jerry Zon Methylated riboA and riboC are the most commonly detected nucleobases in epigenetics research Powerful new analytical methods are key tools for progress Promising PacBio sequencing and novel “Pan Probes” reported    In ...