RNA-Seq Blog Transcriptome Research & Industry News
A research team from CSI Singapore investigated the associations between RNA modifications and clinical outcomes. They developed ModTect to...
Read More »New software unveils the relationships between RNA modifications and cancers
Experimental approaches and computational workflows for systematic mapping and functional interpretation of RNA modifications
In addition to four nucleotides in mRNA modified nucleotides are an essential addition to the standard genetic code in eukaryotes and prokaryotes. Epitranscriptomics has emerged as a new field to study nucleotide modifications in mRNA and examine their impact on ...
Read More »Epitranscriptomics – a rapidly developing field
Modified nucleotides in mRNA are an essential addition to the standard genetic code of four nucleotides in animals, plants, and their viruses. The emerging field of epitranscriptomics examines...
Read More »Quantification of experimentally induced nucleotide conversions in high-throughput sequencing datasets
Methods to read out naturally occurring or experimentally introduced nucleic acid modifications are emerging as powerful tools to study dynamic cellular processes. The recovery, quantification and...
Read More »SLAM-seq – Thiol-linked alkylation for the metabolic sequencing of RNA
Gene expression profiling by high-throughput sequencing reveals qualitative and quantitative changes in RNA species at steady-state but obscures the intracellular dynamics of RNA transcription, processing and decay. Researchers at the Institute of Molecular Biotechnology, Vienna have developed thiol(SH)-linked alkylation for the metabolic ...
Read More »