Predicting causal variants affecting expression using whole genome sequence and RNA-seq from multiple human tissues

November 28, 2016 Leave a comment 4,185 Views

Genetic association mapping produces statistical links between phenotypes and genomic regions, but identifying the causal variants themselves remains difficult. Complete knowledge of all genetic variants, as provided by whole genome sequence (WGS), will help, but is currently financially prohibitive for ...

A survey of best practices for RNA-seq data analysis

January 28, 2016 Leave a comment 11,308 Views

RNA-sequencing (RNA-seq) has a wide variety of applications, but no single analysis pipeline can be used in all cases. A multi-national team led by researchers from the University of Florida reviews all of the major steps in RNA-seq data analysis, including ...

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Tag Archives: eQTL Mapping

Predicting causal variants affecting expression using whole genome sequence and RNA-seq from multiple human tissues

A survey of best practices for RNA-seq data analysis

AAV-Perturb-seq – adeno-associated virus (AAV)-mediated direct in vivo single-cell CRISPR screening

capTEs – Cas9-assisted profiling transposable elements expression sequencing

eSPET-seq – genome-wide probing of eukaryotic nascent RNA structure

DISCERN – deep single-cell expression reconstruction for improved cell clustering and cell subtype and state detection

Advancements in genome sequencing propel global RNA sequencing market growth to 2030

VAX-seq – mRNA vaccine quality analysis using RNA sequencing

Single-cell RNA-sequencing integration analysis revealed immune cell heterogeneity in five human autoimmune diseases