SPIRE – a modular pipeline for eQTL analysis of RNA-Seq data

October 11, 2016 Leave a comment 3,934 Views

The interpretation of genome-wide association study is difficult, as it is hard to understand how polymorphisms can affect gene regulation, in particular for trans-regulatory elements located far from their controlling gene. Using RNA or protein expression data as phenotypes, it ...

Vision from next generation sequencing – Multi-dimensional genome-wide analysis for producing gene regulatory networks

February 12, 2015 Leave a comment 12,966 Views

Genomics and genetics have invaded all aspects of biology and medicine, opening uncharted territory for scientific exploration. The definition of “gene” itself has become ambiguous, and the central dogma is continuously being revised and expanded. Computational biology and computational medicine ...

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Tag Archives: eQTL

SPIRE – a modular pipeline for eQTL analysis of RNA-Seq data

Vision from next generation sequencing – Multi-dimensional genome-wide analysis for producing gene regulatory networks

Mim-tRNAseq – A method that accurately measures the abundance and modification status of different tRNAs

Uncovering the Anti-Myeloma Resistance Files

Long term and short-term effects of RNA fixation on Single Cell RNA Sequencing

Single cell RNA sequencing opens new avenues for eradicating leukaemia at its source

2passtools: two-pass alignment using machine-learning-filtered splice junctions increases the accuracy of intron detection in long-read RNA sequencing

scRNA-Seq reveals a new type of bone cell that may uncover therapeutic targets for a range of skeletal diseases

DEBKS – a tool to detect differentially expressed circular RNA