Improved DNA/RNA sequencing methods reveal complex rearrangement in breast cancer cell’s genome

July 25, 2018 Leave a comment 2,584 Views

In cancer cells, genetic errors wreak havoc. Misspelled genes, as well as structural variations—larger-scale rearrangements of DNA that can encompass large chunks of chromosomes—disturb carefully balanced mechanisms that have evolved to regulate cell growth. Genes that are normally silent are...

SpliceNet: recovering splicing isoform-specific differential gene networks from RNA-Seq data of normal and diseased samples

July 22, 2014 Leave a comment 5,056 Views

Conventionally, overall gene expressions from microarrays are used to infer gene networks, but it is challenging to account splicing isoforms. High-throughput RNA Sequencing has made splice variant profiling practical. However, its true merit in quantifying splicing isoforms and isoform-specific exon ...

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Improved DNA/RNA sequencing methods reveal complex rearrangement in breast cancer cell’s genome

SpliceNet: recovering splicing isoform-specific differential gene networks from RNA-Seq data of normal and diseased samples

Researchers have developed an instrument-free single-cell RNA sequencing using a reversible hydrogel for cell-specific barcoding

Transcriptomic analysis of yeast paves way to more efficient production of 2G ethanol

Upcoming Webinar – RNA-Seq: Enhancing Single-Cell Data & Cell Recovery Rates for Complex Tissue Samples

A dual-purpose polymerase engineered for direct sequencing of pseudouridine and queuosine RNA modifications

RNA sequencing data from The Cancer Genome Atlas reveals a potential new target for head and neck cancer immunotherapy

Benchmarking integration of single-cell differential expression

ZARP – an automated workflow for processing of RNA-seq data