Tag Archives: Evolution

UCLA researchers performed RNA sequencing on 40,000 cells to create a high-resolution single-cell gene expression atlas of developing human cortex, providing the first single-cell characterization of previously uncharacterized cell types, including human subplate neurons, comparisons with bulk tissue, and systematic ...

Next Generation Sequencing (NGS) technologies generate a large amount of high quality transcriptome datasets enabling the investigation of molecular processes on a genomic and...

The yolk sac is phylogenetically the oldest of the extraembryonic membranes. The human embryo retains a yolk sac, which goes through primary and secondary phases of development, but its importance is controversial. Although it is known to synthesize proteins, its ...

Post-transcriptional modifications, such as mRNA editing, have the potential to diversify the proteome. Most animals do not show much mRNA editing that results in a codon change (recoding). However, squid (a member of the cephalopod taxa) were recently shown to ...

RNA-sequencing (RNA-seq) can generate millions of reads to provide clues for analyzing novel or abnormal alternative splicing (AS) events in cells. However, current methods for exploring AS events are still far from being satisfactory. Here, researchers from Zhejiang A & ...

Phenotypic differences among species are often driven by evolutionary adaptations in gene expression, yet many developmental programs and pathways are deeply conserved. Gene expression among homologous genes across vertebrate species and tissues has been explored using microarray and RNA-sequencing (RNA-seq). ...

Winged insects underwent an unparalleled evolutionary radiation, but mechanisms underlying the origin and diversification of wings in basal insects are sparsely known compared with more derived holometabolous insects. In the neopteran species Oncopeltus fasciatus, researchers from Wayne State and Penn ...

Click here to register for free and to view the entire webinar: http://xtalks.com/genomic-know-how.as… Although RNA-Seq is a relatively new methodology, with some of the first transcriptome-wide analyses appearing around 2008, RNA-Seq has rapidly evolved to become a standard assay for ...

Pre-mRNA splicing is a critical step in eukaryotic gene expression that contributes to proteomic, cellular and developmental complexity. Small nuclear (sn)RNAs are core spliceosomal components, however, the extent to which differential expression of snRNA isoforms regulates splicing is completely unknown. ...

(Reuters – By Julie Steenhuysen) – Etienne Simon-Loriere of the Pasteur Institut in Paris has his fingers crossed. He is heading to West Africa on Sunday to inspect blood samples gathered from Ebola patients in Guinea in hopes of tracing ...