Generate transcriptomics data resulting from Prostate Cancer patients exosomes to detect biomarkers indicative of aggressive prostate cancer. This includes handling patient tissue, urine and...
Read More »Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing
Extracellular vesicles (EVs) are intercellular communicators with key functions in physiological and pathological processes and have recently garnered interest because of their diagnostic and...
Read More »Global Exosome Transcriptome Profiling Reveals Biomarkers for Multiple Sclerosis
Accumulating evidence supports a role for exosomes in immune regulation. In this study, researchers from the Medical University of Lodz investigated the total circulating exosome transcriptome in relapsing-remitting multiple sclerosis patients (RRMS) and healthy controls (HC). Next generation sequencing (NGS) ...
Read More »RNA is DNA in action
By Wallace Ravven – Losing a breast or a lung to cancer leaves a scar, both physical and emotional. But even a biopsy to determine if a tumor is cancerous, or to track a tumor’s response to drugs, brings short-term ...
Read More »Small RNA Library Construction for Exosomal RNA Sequencing on the Ion Torrent PGM™ and Ion S5™ System
Next-generation deep sequencing (NGS) technology represents a powerful and innovative approach to profile small RNA. Currently, there are a number of large-scale and benchtop sequencing platforms available on the market. Although each platform is relatively straightforward to operate, constructing cDNA ...
Read More »Exosome Diagnostics Unveils RNA-Seq Technology for Biomarker Detection in Exosomal RNA
Exosome Diagnostics, Inc. in recent partnership with Takeda Pharmaceuticals has produced the industry’s first data demonstrating the power of exosomal RNA (exoRNA) for long RNA sequencing (RNA-Seq). This discovery will enable insight into a patient’s genetic makeup that was previously ...
Read More »Minimally invasive genomic and transcriptomic profiling of visceral cancers by next-generation sequencing of circulating exosomes
The ability to perform comprehensive profiling of cancers at high resolution is essential for precision medicine. Liquid biopsies using shed exosomes provide high-quality nucleic acids to obtain molecular characterization, which may be especially useful for visceral cancers that are not ...
Read More »A Method for Surveying the Long-RNA Landscape of Exosomes
The emergence of next-generation sequencing platforms has enabled the discovery and interrogation of RNA from tissues, biofluids, and extracellular vesicles at remarkable levels. Recently, interest has grown in sequencing RNA found in extracellular vesicles called exosomes, because of their role ...
Read More »iSRAP – a one-touch research tool for rapid profiling of small RNA-seq data
Small non-coding RNAs have been significantly recognized as the key modulators in many biological processes, and are emerging as promising biomarkers for several diseases. These RNA species are transcribed in cells and can be packaged in extracellular vesicles, which are ...
Read More »RNA-Seq and Digital PCR for Liquid Biopsies
The Third Annual SELECTBIO Circulating Biomarkers World Congress 2016 brings together academic researchers as well as industry participants to present and discuss the most up-to-date research and commercial activities in the translation of various circulating biomarker classes towards the clinic.The ...
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