Extracellular RNAs (exRNAs) in biofluids have attracted great interest as potential biomarkers. Although extracellular microRNAs in blood plasma are extensively characterized, extracellular...
Read More »Comparison of reproducibility, accuracy, sensitivity, and specificity of miRNA quantification platforms
Given the increasing interest in their use as disease biomarkers, the establishment of reproducible, accurate, sensitive, and specific platforms for...
Read More »exceRpt – a comprehensive analytic platform for extracellular RNA profiling
Small RNA sequencing has been widely adopted to study the diversity of extracellular RNAs (exRNAs) in biofluids; however, the analysis of exRNA samples...
Read More »RNA-Seq reveals large differences in small RNA composition between human biofluids
Extracellular microRNAs (miRNAs) and other small RNAs are implicated in cellular communication and may be useful as disease biomarkers. UCSF researchers systematically compared small RNAs in 12 human biofluid types using RNA sequencing...
Read More »TIGER – bioinformatic analysis of endogenous and exogenous small RNAs
To comprehensively study extracellular small RNAs (sRNA) by sequencing (sRNA-seq), researchers at the Vanderbilt University Medical Center developed a novel pipeline to overcome current limitations in analysis entitled, "Tools for Integrative Genome analysis...
Read More »TGen study of ASU football team produces largest known RNA sequencing dataset for concussion diagnostics
TGen-Riddell partnership could help lead to advanced methods of injury and disease detection Following a three-year study of the Arizona State University football program, researchers at the Translational Genomics Research Institute (TGen) have created the largest dataset to date of ...
Read More »Fighting veterinary drug abuse with RNA-Seq
Worldwide growth and performance-enhancing substances are used in cattle husbandry to increase productivity. In certain countries however e.g., in the EU, these practices are forbidden to prevent the consumers from potential health risks of substance residues in food. To maximize ...
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