Extracellular vesicles (EVs) are intercellular communicators with key functions in physiological and pathological processes and have recently garnered interest because of their diagnostic and...
Read More »RNA-Seq and Digital PCR for Liquid Biopsies
The Third Annual SELECTBIO Circulating Biomarkers World Congress 2016 brings together academic researchers as well as industry participants to present and discuss the most up-to-date research and commercial activities in the translation of various circulating biomarker classes towards the clinic.The ...
Read More »RNA-Seq reveals distinct features of exosomal small RNA
Functional biomolecules, including small noncoding RNAs (ncRNAs), are released and transmitted between mammalian cells via extracellular vesicles (EVs), including endosome-derived exosomes. The small RNA composition in cells differs from exosomes, but underlying mechanisms have not been established. Researchers from the ...
Read More »The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling
Despite an enormous interest in the role of extracellular vesicles, including exosomes, in cancer and their use as biomarkers for diagnosis, prognosis, drug response and recurrence, there is no consensus on dependable isolation protocols. Now, researchers at Ghent University Hospital ...
Read More »Analysis of the RNA content of the exosomes derived from blood serum and urine and its potential as biomarkers
Exosomes are tiny vesicles (30-150 nm) constantly secreted by all healthy and abnormal cells, and found in abundance in all body fluids. These vesicles, loaded with unique RNA and protein cargo, have a wide range of biological functions, including cell-to-cell ...
Read More »Next Generation Sequencing: Research to Clinic Conference
SELECTBIO is hosting its Next Generation Sequencing: Research to Clinic Conference to bring together delegates from around the world focusing on technology development, informatics/data analysis, and applications of next generation sequencing (NGS) in various research fields and the migration of ...
Read More »